Synthesis of Dihydroindolo[2,3-c]carbazole as Potential Telomerase Inhibitor
Abstract: The dictyodendrins A-E were the first marine natural products that show inhibition of telomerase. A versatile and convergent route was described for the synthesis of derivatives of these pyrrolo[2,3-c]carbazole alkaloids as potential inhibitors of telomerase, by cyclotrimerization [2 + 2 + 2] of ruthenium-catalyzed diynamides diarylacetylenes.
Author(s): Carvajal-Miranda, Y; Perez-Salazar, R; Varela, JA
JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume: 53 Pages: 762-766 Published: MAY 2016
PDF: Synthesis of Dihydroindolo[2,3-c]carbazole as Potential Telomerase Inhibitor
DOI: 10.1002/jhet.2333
