Synthesis of Dihydroindolo[2,3-c]carbazole as Potential Telomerase Inhibitor

JOURNAL OF HETEROCYCLIC CHEMISTRY

31 de maio de 2019 LAbI UFSCar Artigo 0

Synthesis of Dihydroindolo[2,3-c]carbazole as Potential Telomerase Inhibitor

Abstract: The dictyodendrins A-E were the first marine natural products that show inhibition of telomerase. A versatile and convergent route was described for the synthesis of derivatives of these pyrrolo[2,3-c]carbazole alkaloids as potential inhibitors of telomerase, by cyclotrimerization [2 + 2 + 2] of ruthenium-catalyzed diynamides diarylacetylenes.

Author(s): Carvajal-Miranda, Y; Perez-Salazar, R; Varela, JA

JOURNAL OF HETEROCYCLIC CHEMISTRY

Volume: 53 Pages: 762-766 Published: MAY 2016

PDF: Synthesis of Dihydroindolo[2,3-c]carbazole as Potential Telomerase Inhibitor

DOI: 10.1002/jhet.2333

Sobre LAbI UFSCar 2924 Artigos
O Laboratório Aberto de Interatividade para Disseminação do Conhecimento Científico e Tecnológico (LAbI), vinculado à Universidade Federal de São Carlos (UFSCar), é voltado à prática da divulgação científica pautada na interatividade; nas relações entre Ciência, Arte e Tecnologia.
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