Writers: Lima, A. E. B., Luz, G. E., Batista, N. C., Longo, E., Cavalcante, L. S., Santos, R. S.
Keywords: Amperometric Sensor; Gold microelectrode array; Ethambutol
Abstract: In this paper, gold microelectrode array (Au-MEA) were employed to determination of ethambutol in aqueous medium. Au-MEA was constructed with an electronic microchip integrated circuit. The standard curve (analytical curve) was constructed for a single microelectrode (ME) in a concentration range of 5.0×10−5 to 2.0×10−3 mol L−1, allowing estimation of both the limit of detection (LOD) (4.73×10−5 mol L−1) and the limit of quantification (LOQ) (1.57×10−4 mol L−1) for ethambutol. When the MEA was utilized, the LOD and LOQ were 1.55×10−7 and 5.18×10−7 mol L−1, respectively. Our results indicated that Au-MEA can be utilized as amperometric sensors for ethambutol determination in aqueous media.