Determination of Ethambutol in Aqueous Medium Using an Inexpensive Gold Microelectrode Array as Amperometric Sensor

Electroanalysis, Volume 28, Issue 5 May 2016 Pages 985–989

Figure: SWV curves registered increasing the number of gold microelectrodes (gold microelectrode array) in ethambutol solution fixed in 1.5 mmolL-1(f=20 s-1, a=25 mV, and ΔEs=2 mV).

[otw_shortcode_button href=”http://cdmf.org.br/website/wp-content/uploads/2016/11/Lima-2016-Determination-of-Eth.pdf” size=”large” icon_type=”general foundicon-down-arrow” icon_position=”left” shape=”square” color_class=”otw-red” target=”_blank”]See PDF[/otw_shortcode_button] [otw_shortcode_button href=”http://dx.doi.org/10.1002/elan.201500600″ size=”large” icon_type=”general foundicon-page” icon_position=”left” shape=”square” color_class=”otw-green” target=”_blank”]Full Length Article[/otw_shortcode_button]

Writers: Lima, A. E. B., Luz, G. E., Batista, N. C., Longo, E., Cavalcante, L. S., Santos, R. S.

Keywords: Amperometric Sensor; Gold microelectrode array; Ethambutol

Abstract: In this paper, gold microelectrode array (Au-MEA) were employed to determination of ethambutol in aqueous medium. Au-MEA was constructed with an electronic microchip integrated circuit. The standard curve (analytical curve) was constructed for a single microelectrode (ME) in a concentration range of 5.0×10−5 to 2.0×10−3 mol L−1, allowing estimation of both the limit of detection (LOD) (4.73×10−5 mol L−1) and the limit of quantification (LOQ) (1.57×10−4 mol L−1) for ethambutol. When the MEA was utilized, the LOD and LOQ were 1.55×10−7 and 5.18×10−7 mol L−1, respectively. Our results indicated that Au-MEA can be utilized as amperometric sensors for ethambutol determination in aqueous media.

Sobre CDMF 591 Artigos
O CDMF é um dos Centros de Pesquisa, Inovação e Difusão (CEPID) apoiados pela FAPESP. O Centro também recebe investimento do CNPq, a partir do Instituto Nacional de Ciência e Tecnologia dos Materiais em Nanotecnologia (INCTMN).