O doutor Wojtek Chrzanowski ministra palestra no dia 13 de setembro, a partir das 14 horas na Faculdade de Odontologia da Unesp de Araraquara. A palestra é intitulada “Biointerfaces – art and science at nanoscale” e acontecerá no Auditório da Odontologia, localizado no 6o andar. As inscrições podem ser feitas aqui e haverá entrega de certificado.
Nanosafety
Safety of nanomaterials, which are virtually everywhere including cosmetics, toiletries, food products including sweets, chewing gum etc., vitamins, and drugs is of a colossal concern. There is already evidence that nanomaterials may induce seriously health problems and their effects on living organisms are largely unexplored. Dr Chrzanowski research develops functional tissue models of both healthy and diseased tissues to provide a deep understanding of nanomaterial interactions in biological environment. Furthermore, this new knowledge allows him to develop new classes of non-toxic nanomaterials and theranostics that may be used safely for diagnostic and therapeutic application i.e. controlled and targeted drug delivery.
Stem cells and exosomes delivery – a holistic approach for multifaceted lung tissue repair. Dr Chrzanowski laboratory develops a frontier cell- and exosome-based approach targeted at lung diseases. Dr Chrzanowski laboratory develops a frontier cell- and exosome-based approach targeted at lung diseases. In the area of drug delivery,his work is cantered on delivery systems that are capable of modulating drug uptake. In particular his develops stimuli-responsive materials that can target disease tissue and releasetherapeutic cargolocally upon external activation. Drug carriers are design to sensitise cells and upregulate drug adsorption.
Drug delivery
Dr Chrzanowski work focuses on drug delivery systems that are capable of modulating drug uptake. In particular his research centres around stimuli-responsive materials that can target disease tissue and release drug locally upon external activation. Drug carriers are design to sensitise cells and upregulate drug adsorption.
Nano-bio-characterisation
Dr Chrzanowski laboratory applies a multifaceted system approach to examine material characteristic at nanoscale to gain fundamental understanding of cellular responses and modulation. He have assembled an unparalleled suite of microscopy systems (of which three are unique to the Asia Pacific region) dedicated to bio-nano-characterisation experiments, which includes: molecular force probe (MFP-3d-BIO), three atomic force microscopes which feature advanced nanomechanical operation modes (PeakForce QNM, Amplitude Modulated Force Microscopy), nano Infra-Red spectroscopy system (nanoIR, ANASYS), Lorenz Contact Resonance microscope, 3D cell explorer (Nanolive), inverse gas chromatography (IGC), ATR-FTIR, qNano (scanning ion occlusion sensing system), Surface Plasmon Resonance spectroscope (SPR), ElastoSensBio2 and surface energy analysers. The facility include also state-of-the-art cell culture laboratory equipped with IncuCyte (build in microscopy system in the incubator for continuous life cell imaging), flow cytometery, high-resolution fluorescent microscopy and qPCR.
